skip to main content

Optimizing Propylene Glycol Purity and Profitability through Variations in Reactor Temperature and Distillation

Department of Chemical Engineering, Faculty of Engineering, Universitas Diponegoro, Semarang, Central Java 50275, Indonesia

Received: 12 Dec 2025; Revised: 19 Dec 2025; Accepted: 22 Dec 2025; Available online: 6 Jan 2026; Published: 30 Jun 2026.
Editor(s): Istadi Istadi
Open Access Copyright (c) 2026 by Authors, Published by Universitas Diponegoro and BCREC Publishing Group
Creative Commons License This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Fulltext View|Download

Citation Format:
Cover Image
Abstract

Propylene glycol (PG) is a multifunctional diol widely used in food, pharmaceutical, cosmetic, and chemical industries due to its favorable physicochemical properties, high water solubility, and low toxicity. This study examines PG production through non-catalytic hydration of propylene oxide, focusing on the effect of reactor inlet temperature on process efficiency and economic performance. In the process, propylene oxide and water are mixed and fed into a continuous stirred-tank reactor (CSTR), followed by distillation for product purification. Temperature variations from 23.9 °C to 80 °C were analyzed to determine their impact on conversion and profitability. At 23.9 °C, the process was economically unfavorable, yielding a negative profit of –161.09 $/hour. Increasing the inlet temperature to 40 °C significantly improved conversion and distillation efficiency, resulting in a profit of 191.09 $/hour (552,689 $/year). Further temperature increases provided no additional economic benefit and increased energy demand. Therefore, 40 °C is recommended as the optimal operating condition, offering the best balance between technical performance and profitability. Copyright © 2026 by Authors, Published by Universitas Diponegoro and BCREC Publishing Group. This is an open access article under the CC BY-SA License (https://creativecommons.org/licenses/by-sa/4.0).

Keywords: Propylene glycol; Distillation; Purity; CSTR; Temperature

Article Metrics:

  1. Alshbuki, E. (2023). Simulation of The Optimum Operating Conditions for A Propylene Glycol Production Unit Using Aspen Hysys Software. Journal of Pure & Applied Sciences, 22(3), 120–123. DOI: 10.51984/jopas.v22i3.2758
  2. Okolie, J.A. (2022). Insights on production mechanism and industrial applications of renewable propylene glycol. ISCIENCE, 25, 104903. DOI: 10.1016/j.isci.2022.104903
  3. Pemberton, MA., Kimber, I. (2023). Propylene glycol, skin sensitisation and allergic contact dermatitis: A scientific and regulatory conundrum. Regulatory Toxicology and Pharmacology, 138. DOI: 10.1016/j.yrtph.2023.105341
  4. Duggan, K., Ijaz, M.K., McKinney, J., Maillard, J.Y. (2024). Reviewing the evidence of antimicrobial activity of glycols. Journal of Applied Microbiology, 135. DOI: 10.1093/jambio/lxae071
  5. Wordu, A.A., Wosu, C.O. (2019). CSTR Design for Propylene Glycol Chemical Production. International Journal of Latest Technology in Engineering. 8(2)
  6. Fendu, E.M., Nicolae, M. (2020). Synthesis and simulation of a distillation columns system for the propylene glycols mixtures separation. Engineering Reposrts, 3(4), 1-20. DOI: 10.1002/eng2.12301
  7. Ariyanto, E., Yusmartini, E.S., Robiah, R., Ardianto, F. (2024). Simulation Study of Propylene Glycol Formation from Propylene Oxide and Water: Effect of Reactor Type, Reactant Ratio, Temperature, and Reactor Configuration. Indonesian Journal of Fundamental and Applied Chemistry, 9(1), 26–34. DOI: 10.24845/ijfac.v9.i1.26
  8. Akyalcin, S. (2017). Kinetika hidratacije propilen-oksida u prisustvu heterogenog katalizatora. Chemical Industry and Chemical Engineering Quarterly, 23(4), 573–580. DOI: 10.2298/CICEQ170203011A
  9. Hu, S., Li, J., Wang, Q., Yang, W. (2022). Design and optimization of an integrated process for the purification of propylene oxide and the separation of propylene glycol by-product. Chinese Journal of Chemical Engineering, 45, 111–120. DOI: 10.1016/j.cjche.2021.04.012
  10. Azad, T., Torres, H.F., Auad, M.L., Elder, T., Adamczyk, A.J. (2021). Isolating key reaction energetics and thermodynamic properties during hardwood model lignin pyrolysis. Physical Chemistry Chemical Physics, 23(37), DOI: 10.1039/d1cp02917g
  11. Yaws, C.L. (1997). Handbook of chemical compound data for process safety : comprehensive safety and health-related data for hydrocarbons and organic chemicals : selected data for inorganic chemicals. Gulf Pub. Co
  12. Valverde, J.L., Ferro, V.R., Giroir-Fendler, A. (2023). Automation in the simulation of processes with Aspen HYSYS: An academic approach. Computer Applications in Engineering Education, 31(2), 376–388. DOI: 10.1002/cae.22589
  13. Cherkasov, N., Adams, S.J., Bainbridge, E.G.A., Thornton, J.A.M. (2022). Continuous stirred tank reactors in fine chemical synthesis for efficient mixing, solids-handling, and rapid scale-up. Reaction Chemistry and Engineering, 8, 266–277. DOI: 10.1039/d2re00232a
  14. Li, M.R., Gu, G.G., Yue, T.J., Ren, W.M., Lu, X.B. (2024). CO2-assisted hydration of propylene oxide to produce propylene glycol: Accessing high selectivity using a jet loop reactor. Journal of CO2 Utilization, 80. DOI: 10.1016/j.jcou.2024.102684
  15. Olivier-Maget, N., Berdouzi, F., Murillo, C., Gabas, N. (2021). Deviation propagation along a propylene glycol process using dynamic simulation: an innovative contribution to the risk evaluation. Journal of Loss Prevention in the Process Industries, 70, 104435. DOI: 10.1016/j.jlp.2021.104435
  16. Sun, P., Zhang, W., Yu, X., Zhang, J., Xu, N., Zhang, Z., … Jin, X. (2022). Hydrogenolysis of Glycerol to Propylene Glycol: Energy, Tech-Economic, and Environmental Studies. Frontiers in Chemistry, 9. DOI: 10.3389/fchem.2021.778579
  17. Shao, Y., Xiao, H., Chen, B., Huang, S., Qin, F.G.F. (2018). Comparison and analysis of thermal efficiency and exergy efficiency in energy systems by case study. Energy Procedia, 153, 161–168. DOI: 10.1016/j.egypro.2018.10.081
  18. Muranaka, Y., Maki, T., Nakayoshi, D., Ota, M., Mae, K. (2024). Temperature control strategy for safer and heat-efficient operations in a catalytic flow reactor. Chemical Engineering Journal, 491. DOI: 10.1016/j.cej.2024.152029
  19. Restrepo, J.B., Paternina-Arboleda, C.D., Bula, A.J. (2021). 1,2—propanediol production from glycerol derived from biodiesel’s production: Technical and economic study. Energies, 14(16). DOI: 10.3390/en14165081
  20. Chong, D.J.S., Foo, D.C.Y., Putra, Z.A. (2023). A reduced order model for triethylene glycol natural gas dehydration system. South African Journal of Chemical Engineering, 44, 51–67. DOI: 10.1016/j.sajce.2023.01.001

Last update:

No citation recorded.

Last update:

No citation recorded.