Enolisation Kinetics of m-Nitro Acetophenone

Swati Malhotra Swati Malhotra; Dipika Jaspal

doi:10.9767/bcrec.9.1.5258.16-22

DOI: https://doi.org/10.9767/bcrec.9.1.5258.16-22

Enolisation Kinetics of m-Nitro Acetophenone

Swati Malhotra Swati Malhotra¹, Dipika Jaspal²

¹Department of Chemistry, SLP Science College Gwalior, Madhya Pradesh, India

²Department of Applied Science, Symbiosis Institute of Technology, Symbiosis International University, Lavale, Pune, Maharashtra, India

Received: 31 Jul 2013; Revised: 8 Nov 2013; Accepted: 21 Nov 2013; Available online: 12 Mar 2014; Published: 30 Apr 2014.

Editor(s): Istadi Istadi

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Abstract

m-Nitroacetophenone was chosen for the study of kinetics of enolisation. The rate of the reaction was studied by iodination. The kinetics of the reaction was monitored under several conditions of variation of ketone concentration, dielectric constant of the medium , temperature, effect of catalyst etc. In addition to this four different amino acids viz. β-alanin, DL-alanin, L-alanin and Glycine were tested as catalyst for the enolisation process. The rate of enolisation was found to increase with the increase in then ketone concentration , percentage composition of the solvent mixture and also with the increase in the dipole moments of the amino acids. Pseudofirst order rate kinetics was operational and the rate constants were found to increase with the increase in the amino acid molarity. Linear plots obtained for log of rate constants versus reciprocal of temperature which were in good agreement with Arrhenius equation. The values of thermodynamic parameters like Entropy (∆S≠) , Enthalpy (∆H≠), energy of activation (∆Ea) and Free energy(∆F≠) were calculated and were found to be 2.6186 e.u. , 20.85 e.u. ,23.46 k cal mol-1 and 20.0 k cal mol-1 respectively. © 2014 by Authors, Published by BCREC Group. This is an open access article under the CC BY-SA License (https://creativecommons.org/licenses/by-sa/4.0)

Keywords: Amino Acids; Catalysis; Enolisation ; Kinetics ; m-Nitro acetophenone

Funding: CSIR India

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Section: Original Research Articles

Language : EN

In 2014: BCREC Volume 9 Issue 1 Year 2014 (April 2014)

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